Research guide
Pinealon
Pineal peptide bioregulator for circadian rhythm and neuroprotection research. ≥98% purity, COA. RUO only.
Short answer
Pinealon is supplied by HALO as a research-use-only lyophilized compound for qualified laboratory research. Pineal peptide bioregulator for circadian rhythm and neuroprotection research. ≥98% purity, COA. RUO only.
- Documentation: 98%+ HPLC purity, independent COA, lot-indexed records
- Use limitation: Research use only; not for human or veterinary use
Diagrams
Mechanism of action in research models
Pinealon is used in longevity, mitochondrial, immune-modulatory, and cellular stress research programmes. Typical endpoints include mitochondrial membrane potential, ROS production, NAD+/NADH ratios, senescence-associated markers, and innate immune signalling in cell culture or animal models. Mitochondria-targeted peptides may interact with cardiolipin or inner-membrane components; thymic peptides modulate T-cell differentiation pathways in immunology research.
All HALO longevity-cluster materials are RUO reference compounds. Experimental design should separate biochemical mechanism data from any clinical extrapolation.
Research background
Longevity research increasingly relies on well-characterised peptide tool compounds with documented purity and identity. Pinealon is supplied with independent COA verification so laboratories can cite batch-specific analytical data in methods sections and procurement audits.
Documentation and COA standards
Each HALO lot of Pinealon ships with an independent certificate of analysis documenting:
- HPLC purity — reverse-phase chromatography with ≥98% main peak by area integration
- Identity confirmation — LC-MS, ESI-MS, or MALDI-TOF as applicable to molecular weight
- Lot / batch number — must match the vial label for procurement audit trails
- Test date and method — third-party laboratory, not supplier self-reporting
Read: What is a peptide COA? · Batch-specific verification · Lab results index
Storage and handling
Store lyophilized Pinealon sealed, cold (−20 °C), dry, and protected from light until reconstitution. After reconstitution with an appropriate research diluent, follow institutional stability protocols; minimise freeze-thaw cycles and document open-vial dates in the lab log.
Tools: Peptide calculator · Lyophilized peptide guide · Stability guide
Frequently asked research questions
What is Pinealon used for in research?
What documentation ships with Pinealon?
How is purity verified for Pinealon?
What does RUO mean for this listing?
How should lyophilized Pinealon be stored?
Where can the COA be verified?
Selected references
- Szeto HH. “Mitochondria-targeted peptide antioxidants.” Pharmacol Rev. 2014;66(1):1-13. PMID: 24381208
- Miller RA, et al. “NAD+ in aging and disease.” Science. 2023;382(6672):eabi4832. DOI: 10.1126/science.abi4832
Research use only. Materials are sold strictly for in vitro and qualified laboratory research. Not for human or veterinary use, diagnosis, or treatment. Full text: Research Use Statement.