Description
PE-22-28 is a synthetic derivative of spadin, a TREK-1 potassium channel antagonist, used in neuroscience research examining synaptic plasticity, BDNF signalling, and neurogenesis in preclinical models. TREK-1 channels regulate neuronal excitability; PE-22-28 is studied as a tool compound for modulating these pathways in hippocampal and cortical research contexts.
Available as 5 mg lyophilized at ≥98% purity with COA.
| Format | Lyophilized powder |
|---|---|
| Purity | ≥98% HPLC |
| Storage | −20°C desiccated |
Research Use Only. Not for human or veterinary use.




